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Women's Health

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Action Plan

Breast cancer screening for those under 40.

By Dr. Karen LanePublished: September, 2006

Breast cancer screening for those under 40

Breast  cancer affects more than 200,000 women in the United States each year,  and approximately 5% of these cases are women under the age of 40. While  this number is low, there are certain situations that may result in a young woman being at high risk for the development of breast cancer at  an early age. These include:

    •     Women with a mother or sister with breast cancer, particularly at an early age.
    •     Women  with a family history of multiple relatives with cancer (especially breast and ovarian) on either side of the family.
    •     Women who have had a biopsy that showed  some abnormal cells that were not yet  considered cancerous.

It has recently been discovered that there are breast  cancer genes, BRCA1 and BRCA2 that are associated with a high likelihood  of developing  breast and/or  ovarian cancer. However, only about 5-10% of all breast cancer is hereditary.  Women who have a strong family history should talk to their physician about  the need for a consultation with a genetic counselor who can accurately  assess a  woman’s risk for developing cancer and determine whether they should be  tested for a mutation of one of these breast cancer genes.

The National Cancer  Institute has set specific guidelines regarding the number of relatives with cancer, type of cancer and age at diagnosis that would justify  testing a woman for the BRCA1 or BRCA2 gene mutation.

Screening for high-risk women
For women considered at high risk for developing breast cancer, a clinical  breast exam by a physician should be obtained every six months along with an  annual  mammogram. If a woman has a mother or a sister with breast cancer, she should  start getting mammograms 10 years before the age that her relative was diagnosed. For example, if a woman’s mother was diagnosed with breast cancer at age  45, the daughter should start getting mammograms at age 35.

MRI is a relatively  new type of imaging that is often used for women who are considered to be high  risk due to their family history. However, MRI is not widely used as a screening tool for the general population.

Screening for the general population
For women with no family history of breast cancer and no personal history of abnormal breast biopsies, the screening recommendations are:
    •     Annual clinical  breast exams to look for any lumps or nipple discharge starting  at age 18;
    •      Annual mammograms starting at age 40.
    •     In very young women (under 30), mammography  is often not very helpful because of the density of their breast tissue.  In fact, there is some concern that mammography  can actually be harmful to the breast tissue in women in their late teens  and early 20s. If a lump is discovered in a young patient, an ultrasound  is often  used to determine whether the lump requires a biopsy.

There has been much debate  about the role of breast self-exams in the detection of breast cancer. It is  advisable for a woman to perform a breast exam once a month possibly while in the shower to look for any changes, including new lumps. If a new lump is felt, it is important to see a physician to evaluate this  lump. The overwhelming majority of lumps in women under 40 will be benign  (noncancerous). However, in most cases it is important to confirm this with a needle biopsy.

Being proactive about breast health is the best defense  for women who are at high risk for breast cancer. It is encouraging to  note that even if breast cancer  is detected, today’s treatments are better than ever before and offer a  high likelihood of effectively treating this common disease.m

Dr. Karen Lane  is an oncologic surgeon specializing in breast cancer at UCI Medical Center.  Information: 877.UCI.DOCS.

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